How It Works

When the ProBiora3™ ingredient enters the mouth and contacts saliva, the freeze-dried probiotics activate and attach themselves to the teeth and gum tissue, establishing Colony Forming Units (CFU) of live, active bacteria both on the surface of the teeth and deep beneath the gum line. These colonies compete for both nutrients and space with the opportunistic bacteria known to be linked to pathogenic activity in the mouth. With daily replenishment, the ProBiora3 bacteria re-establish the natural microbial balance in the mouth and create whiter teeth, fresher breath and healthier teeth and gums.

In the oral cavity, opportunist harmful bacteria convert sugar and carbohydrates into lactic acid. Lactic acid is the bacterial byproduct which is responsible for dental caries and the erosion of tooth enamel. The Standard American Diet promotes the ongoing conversion to lactic acid by providing a constant source of simple carbohydrates for bacterial cell growth, thus creating an even greater imbalance in oral microflora. Eating a healthy diet contributes about 50 percent to the overall health of the oral cavity. As such, the Standard American Diet is a key contributor to periodontal disease that can strike up to 75 percent of the population at some point in their lives. Without requiring lifestyle changes, the addition of the ProBiora3 probiotic ingredient can quickly, dramatically and painlessly affect the long term health and wellness of the mouth and the other health systems dependent on oral health. If oral health is managed with ProBiora3 supplementation daily, the majority of the population could greatly minimize the effects of this serious, costly and painful condition.

One unique strain of beneficial flora used in ProBiora3 is lactic-acid deficient and can promote healthier teeth. A byproduct of the other two strains is a natural low dose of hydrogen peroxide, which safely promotes healthier gums, fresher breath and whiter teeth.

Contact Oragenics today to learn how to incorporate this innovative formulation into your products!



With daily replenishment, the ProBiora3 bacteria re-establish the natural microbial balance in the mouth and create whiter teeth, fresher breath and healthier teeth and gums.

Delivery Mechanisms

  • Mints & Gums
  • Powders & Gels
  • Dissolvable Strips
  • Frozen Dairy Products
  • Dental Care Products
  • Pet Products
  • And many more!
  • See all ProBiora3 Applications